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Joanne J Lager Selected Research

XL765

4/2018Voxtalisib (XL765) in patients with relapsed or refractory non-Hodgkin lymphoma or chronic lymphocytic leukaemia: an open-label, phase 2 trial.
9/2015Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade glioma.

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Joanne J Lager Research Topics

Disease

2Neoplasms (Cancer)
02/2011 - 01/2010
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
04/2018
1Lymphoma (Lymphomas)
04/2018
1Non-Hodgkin Lymphoma (Lymphosarcoma)
04/2018
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
04/2018
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
04/2018
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
04/2018
1Glioma (Gliomas)
09/2015
1Exanthema (Rash)
02/2011
1Mucositis
02/2011
1Ovarian Neoplasms (Ovarian Cancer)
10/2010
1Carcinoma (Carcinomatosis)
10/2010
1Diarrhea
01/2010
1Rhabdomyosarcoma
07/2006

Drug/Important Bio-Agent (IBA)

2XL765IBA
04/2018 - 09/2015
2pazopanibFDA Link
10/2010 - 01/2010
1Phosphatidylinositols (Phosphatidylinositol)IBA
09/2015
1TOR Serine-Threonine KinasesIBA
09/2015
1Temozolomide (Temodar)FDA LinkGeneric
09/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2011
1Erlotinib Hydrochloride (CP 358,774)FDA Link
02/2011
1EverolimusFDA Link
02/2011
1Bevacizumab (Avastin)FDA Link
02/2011
1PlatinumIBA
10/2010
1Angiogenesis InhibitorsIBA
10/2010
1Paclitaxel (Taxol)FDA LinkGeneric
01/2010
1Transaminases (Aminotransferases)IBA
01/2010
1Doxorubicin (Adriamycin)FDA LinkGeneric
07/2006
1IfosfamideFDA LinkGeneric
07/2006
1Etoposide (VP 16)FDA LinkGeneric
07/2006
1Type I DNA Topoisomerases (Topoisomerase I)IBA
07/2006
1PoisonsIBA
07/2006

Therapy/Procedure

1Radiotherapy
09/2015
1Drug Therapy (Chemotherapy)
10/2010
1Therapeutics
10/2010